Cannabis & Sleep Apnea / Related Issues


Sleep Apnea

Title: Pharmacotherapy Of Apnea By Cannabimimetic Enhancement, The PACE Clinical Trial: Effects Of Dronabinol In Obstructive Sleep Apnea

Key Findings

“These findings support the therapeutic potential of cannabinoids in people with OSA. In comparison to placebo, dronabinol was associated with lower AHI, improved self-reported sleepiness, and greater overall treatment satisfaction.”

Information & Links

Link: Pharmacotherapy Of Apnea By Cannabimimetic Enhancement, The PACE Clinical Trial: Effects Of Dronabinol In Obstructive Sleep Apnea

Year: 2017

DOI: https://doi.org/10.1093/sleep/zsx184

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Title: Intranodose ganglion injections of dronabinol attenuate serotonin-induced apnea in Sprague-Dawley rat

Key Findings

“These findings underscore a therapeutic potential of dronabinol for the treatment of obstructive sleep apnea.”

Information & Links

Link: Intranodose ganglion injections of dronabinol attenuate serotonin-induced apnea in Sprague-Dawley rat.

Year: 2014

DOI: 10.1016/j.resp.2013.10.001

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Title: Proof Of Concept Trial Of Dronabinol In Obstructive Sleep Apnea

Key Findings

“Dronabinol treatment is safe and well-tolerated in OSA patients at doses of 2.5–10 mg daily and significantly reduces Apnea Hypopnea Index in the short-term.”

Information & Links

Link: Proof Of Concept Trial Of Dronabinol In Obstructive Sleep Apnea

Year: 2013

DOI: 10.3389/fpsyt.2013.00001

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