Cannabis & Headaches / Migraines


Headaches / Migraines

Title: Variants In The CNR1 Gene Predispose To Headache With Nausea In The Presence Of Life Stress

Key Findings: “One of the main effects of the endocannabinoid system in the brain is stress adaptation with presynaptic endocannabinoid receptor 1 (CB1 receptors) playing a major role. In summary, the CNR1 gene in interaction with life stress increased the risk of headache with nausea suggesting a specific pathological mechanism to develop migraine, and indicating that a subgroup of migraine patients, who suffer from life stress triggered migraine with frequent nausea, may benefit from therapies that increase the endocannabinoid tone.”

Information & Links

Link: Variants In The CNR1 Gene Predispose To Headache With Nausea In The Presence Of Life Stress

Year: 2016

DOI: 10.1111/gbb.12352

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Title: Hemp For Headache: An In-depth Historical And Scientific Review Of Cannabis In Migraine Treatment

Key Findings: “Endocannabinoid deficiency may underlie migraines.”

Information & Links

Link: Hemp For Headache: An In-depth Historical And Scientific Review Of Cannabis In Migraine Treatment

Year: 2004

DOI: 10.1300/J175v01n02_04

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Title: Effects Of Medical Marijuana On Migraine Headache Frequency In An Adult Population

Key Findings: “The frequency of migraine headache was decreased with medical marijuana use.”

Information & Links

Link: Effects Of Medical Marijuana On Migraine Headache Frequency In An Adult Population

Year: 2016

DOI: 10.1002/phar.1673

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Title: Comprehensive Review of Medicinal Marijuana, Cannabinoids, and Therapeutic Implications in Medicine and Headache: What a Long Strange Trip It's Been …

Key Findings: “Supporting literature suggests a role for medicinal cannabis and cannabinoids in several types of headache disorders including migraine and cluster headache, although it is primarily limited to case based, anecdotal, or laboratory-based scientific research.”

Information & Links

Link: Comprehensive Review of Medicinal Marijuana, Cannabinoids, and Therapeutic Implications in Medicine and Headache: What a Long Strange Trip It's Been …

Year: 2015

DOI: 10.1111/head.12570

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